How does Klenzit C Gel train
1 gram of gel contains 1 mg of Adapalen - active agent.
- propylene glycol;
- disodium edetat;
- methyl parahydroxybenzoate;
- carbomer 940 (karbopol 940);
- sodium hydroxide;
- half-oxameasures 407;
- the water purified.
Medicine is issued in the form of gel for external use.
Packaging contains 1 tuba of 0.1% of gel on 15 g or 30 g.
Pharmacodynamics and pharmacokinetics
Medicine of topical administration gel of Klenzit is intended for treatmentof acne rash. Active agent of drug is derivative retinoid - adapalene,showing anti-inflammatory and comedonolytic activity. Adapalene takes part in normalization of processes of an epidermal differentiation and keratinization, slows down formation of microcomedones and reduces manifestations of inflammatory process.
The mechanism of effect of active agent of drug of Klenzit consists in its ability to influence specific gamma receptors of cells of epidermis of integuments, lowering their linked surface in mouths of grease and hair follicles.
The conducted researches in vivo and in vitro proved that Adapalen possesses the expressed antiinflammatory action, due to the influence on factors of inflammatory process. Oppresses a metabolism of arachidonic acid and migration of leukocytes.
At external use of gel system absorption of its active agent of Adapalenquite low, about 4% of the used dose.
From a system of blood-groove to be removed by a liver.
Indications to use
Acne rash (acne).
- hypersensitivity to adapalene and other ingredients of drug;
- lactation period;
- pregnancy period.
With care apply at eczema and dermatitis.
Therapy using gel of Klenzit is generally transferred well. In rare instances observed a hyperemia, irritations, peelings of integuments. In case of these complications recommend to suspend temporarily therapy, with resuming after disappearance of these effects.
Isolated cases development of allergic manifestations which were the reason of full cancellation of treatment are described.
Application instruction (way and dosage)
Drug is used exclusively locally (outwardly).
Before putting gel, the instruction to Klenzit recommends to clear and dry problem sites of integuments of the person carefully.
Easy contacts evenly to distribute gel on the surfaces struck with eels. It is necessary to apply drug of Klenzit 1 time a day, it is the best of all in the evening, at the same time trying not to touch a nasal cavity and a mouth, and also mucous an eye.
The therapeutic effect is observed in 1-2 months after an initiation of treatment and reaches a lasting positive effect after carrying out 3-month therapy.
In rare instances, because of the passing irritation of integuments, treatment can be suspended before disappearance of symptoms of irritation.
After consultation with the attending physician purpose of a repeated course of therapy is possible.
At external use of drug overdose is improbable.
In case of accidental internal reception of gel carry out standard therapy with a gastric lavage and purpose of enterosorbents.
When putting medicine of Klenzit in the evening, use of other antiacne drugs the next morning is admissible.
Simultaneous use of gel of Klenzit and means with the drying and irritating properties (cologne, spirit solutions) is not recommended.
Joint appointment from Benzoyl is allowed by peroxide and clindamycin.
Terms of sale
According to the recipe.
At a temperature not above 25 ° C.
Period of validity
In case of accidental hit of medicine in an oral cavity and a nose, and also on mucous an eye, it is necessary to wash out with special care them warm water.
Recommend to avoid influence of direct sunshine on skin sites with the applied gel, because of possible development irritation of skin.
Analogs of drug of Klenzit which can replace it in case of individual sensitivity to its active agent:
- Klenzit-S 0.1% gel 30gglenmarkFarmasyyutikalz Ltd
- Gel 30gglenmarkFarmasyyutikalz LtdKlenzit 0.1%
- Klenzit-S 0.1% gel 15gglenmarkFarmasyyutikalz Ltd
- Gel 15gglenmarkFarmasyyutikalz LtdKlenzit 0.1%
Drugstore of IFC
- Klenzit gel of 0.1% 15 g, Glenmarkindiya
- Klenzit About gel 0.1% 15 g, Glenmarkindiya
- Klenzit About gel 0.1% 30 g, Glenmarkindiya
- Klenzit gel of 0.1% 30 g, Glenmarkindiya
Education: Graduated from the Vinnytsia national medical university of N.I. Pirogov, pharmaceutical faculty, the higher pharmaceutical education - the specialty "Pharmacist".
Experience: Work in Koneks and Bios-Media pharmacy chains as "Druggist". Work as "Pharmacist" in Avicenna pharmacy chain of the city of Vinnytsia.
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